In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies.
%0 Journal Article
%1 Whiting2011
%A Whiting, Penny F
%A Rutjes, Anne W S
%A Westwood, Marie E
%A Mallett, Susan
%A Deeks, Jonathan J
%A Reitsma, Johannes B
%A Leeflang, Mariska M G
%A Sterne, Jonathan A C
%A Bossuyt, Patrick M M
%D 2011
%J Annals of internal medicine
%K Bias(Epidemiology) Diagnosis Evidence-BasedMedicine Humans PatientSelection QualityControl Questionnaires ReferenceStandards ReviewLiteratureasTopic TimeFactors
%N 8
%P 529-36
%R 10.7326/0003-4819-155-8-201110180-00009
%T QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.
%U http://www.annals.org/content/155/8/529.abstract http://www.ncbi.nlm.nih.gov/pubmed/22007046
%V 155
%X In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies.
@article{Whiting2011,
abstract = {In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies.},
added-at = {2023-02-03T11:44:35.000+0100},
author = {Whiting, Penny F and Rutjes, Anne W S and Westwood, Marie E and Mallett, Susan and Deeks, Jonathan J and Reitsma, Johannes B and Leeflang, Mariska M G and Sterne, Jonathan A C and Bossuyt, Patrick M M},
biburl = {https://www.bibsonomy.org/bibtex/274a3816d54f3a4ab8a3f8b04bd60a0cf/jepcastel},
doi = {10.7326/0003-4819-155-8-201110180-00009},
interhash = {86b31452bdc69b2491036994fa486dd2},
intrahash = {74a3816d54f3a4ab8a3f8b04bd60a0cf},
issn = {1539-3704},
journal = {Annals of internal medicine},
keywords = {Bias(Epidemiology) Diagnosis Evidence-BasedMedicine Humans PatientSelection QualityControl Questionnaires ReferenceStandards ReviewLiteratureasTopic TimeFactors},
month = {10},
note = {6383<m:linebreak></m:linebreak>Proves diagnòstiques; Critical appraisal; Checklist},
number = 8,
pages = {529-36},
pmid = {22007046},
timestamp = {2023-02-03T11:44:35.000+0100},
title = {QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.},
url = {http://www.annals.org/content/155/8/529.abstract http://www.ncbi.nlm.nih.gov/pubmed/22007046},
volume = 155,
year = 2011
}